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5ICT

Crystal structure of the Drosophila GluR1A ligand binding domain Y792T mutant complex with glutamate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate receptor 1polymer26730504.71UniProt (Q03445)
Pfam (PF10613)
Pfam (PF00060)
Drosophila melanogaster (Fruit fly)Glutamate receptor I,dGLUR-I,Kainate-selective glutamate receptor,Glutamate receptor I,dGLUR-I,Kainate-selective glutamate receptor
2B
(A)
GLUTAMIC ACIDnon-polymer147.11Chemie (GLU)
3C, D
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
4E
(A)
waterwater18.0285Chemie (HOH)
Sequence modifications
A: 3 - 123 (UniProt: Q03445)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
A: 126 - 267 (UniProt: Q03445)
PDBExternal DatabaseDetails
Gly 124-linker
Thr 125-linker
Thr 179Tyr 792engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30504.7
Non-Polymers*Number of molecules3
Total formula weight331.3
All*Total formula weight30836.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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