5ICN
HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Metastasis-associated protein MTA1 | polymer | 195 | 22165.8 | 1 | UniProt (Q13330) Pfam (PF01448) Pfam (PF00249) | Homo sapiens (Human) | |
| 2 | B (B) | Histone deacetylase 1 | polymer | 376 | 43204.0 | 1 | UniProt (Q13547) Pfam (PF00850) | Homo sapiens (Human) | HDAC1 |
| 3 | C (C) | GLY-ALA-6A0-ARG-HIS | polymer | 9 | 984.1 | 1 | synthetic construct (Human) | ||
| 4 | D (A) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | Homo sapiens (Human) | ||
| 5 | E (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | Homo sapiens (Human) | ||
| 6 | F, G (B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | Homo sapiens (Human) |
Sequence modifications
A: 162 - 354 (UniProt: Q13330)
| PDB | External Database | Details |
|---|---|---|
| Gly 160 | - | expression tag |
| Ala 161 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66353.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 803.6 | |
| All* | Total formula weight | 67157.6 |
