5IA5
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with golvatinib (E7050)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | B (A) | golvatinib | non-polymer | 633.7 | 1 | Chemie (GV0) | Homo sapiens | ||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | Homo sapiens | ||
| 4 | F (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34462.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 819.9 | |
| All* | Total formula weight | 35282.7 |
