5IA1
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with MLN8054
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) In PDB | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | A | 4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID | non-polymer | 476.9 | 1 | Chemie (ZZL) | Homo sapiens | ||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | Homo sapiens | ||
| 4 | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34462.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 538.9 | |
| All* | Total formula weight | 35001.8 |
