5I7Q

Crystal structure of Fkbp12-IF(SlpA), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlpA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Peptidyl-prolyl cis-trans isomerase FKBP1A,FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase,Peptidyl-prolyl cis-trans isomerase FKBP1A	polymer	162	18123.5	1	UniProt (P62942) UniProt (P0AEM0) Pfam (PF00254) In PDB	Homo sapiens (Human)	PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase,PPIase,Rotamase,PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase
2		water	water		18.0	258	Chemie (HOH)

Sequence modifications

A: 1 - 83 (UniProt: P62942)

PDB	External Database	Details
Ala 22	Cys 23	engineered mutation

A: 84 - 143 (UniProt: P0AEM0)
A: 144 - 155 (UniProt: P62942)

PDB	External Database	Details
Ala 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18123.5
All*	Total formula weight	18123.5

*Water molecules are not included.