5I7P

Crystal structure of Fkbp12-IF(SlyD), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlyD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Peptidyl-prolyl cis-trans isomerase FKBP1A,FKBP-type peptidyl-prolyl cis-trans isomerase SlyD,Peptidyl-prolyl cis-trans isomerase FKBP1A	polymer	161	18105.4	1	UniProt (P62942) UniProt (P0A9K9) Pfam (PF00254)	Homo sapiens (Human)	PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase,PPIase,Histidine-rich protein,Metallochaperone SlyD,Rotamase,Sensitivity to lysis protein D,WHP,PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase
2	B (A)	water	water		18.0	205	Chemie (HOH)

Sequence modifications

A: 1 - 83 (UniProt: P62942)

PDB	External Database	Details
Ala 22	Cys 23	engineered mutation

A: 84 - 143 (UniProt: P0A9K9)
A: 144 - 154 (UniProt: P62942)

PDB	External Database	Details
Ala 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18105.4
All*	Total formula weight	18105.4

*Water molecules are not included.