5I67
Crystal Structure Analysis of MTB PEPCK mutant C273S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphoenolpyruvate carboxykinase [GTP] | polymer | 605 | 67176.6 | 1 | UniProt (A5TYT6) Pfam (PF17297) Pfam (PF00821) | Mycobacterium tuberculosis H37Ra | PEPCK,GTP-dependent phosphoenolpyruvate carboxykinase,GTP-PEPCK |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | C, D, E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) PubChem (8117) | |||
| 4 | F, G (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 5 | H (A) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A: 2 - 605 (UniProt: A5TYT6)
| PDB | External Database | Details |
|---|---|---|
| Ser 273 | Cys 273 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 67176.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 871.4 | |
| All* | Total formula weight | 68048.1 |
