5I5X
X-RAY CRYSTAL STRUCTURE AT 1.65A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A THIAZOLE COMPOUND AND PMP COFACTOR.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Branched-chain-amino-acid aminotransferase, mitochondrial | polymer | 369 | 41725.4 | 2 | UniProt (O15382) Pfam (PF01063) | Homo sapiens (Human) | BCAT(m),Placental protein 18,PP18 |
| 2 | C, R (A, B) | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE | non-polymer | 248.2 | 2 | Chemie (PMP) | |||
| 3 | D, S (A, B) | 5-methyl-4-oxo-N-(1,3,4-thiadiazol-2-yl)-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamide | non-polymer | 293.3 | 2 | Chemie (68C) | |||
| 4 | E, F, G, T, U... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 5 | H, I, J, K, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 6 | AA, BA, P, Q, Z (B, A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | CA, DA (A, B) | water | water | 18.0 | 1062 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 365 (UniProt: O15382)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83450.8 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2438.9 | |
| All* | Total formula weight | 85889.7 |
