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5I29

TAF1(2) bound to a pyrrolopyridone compound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transcription initiation factor TFIID subunit 1polymer14416576.61UniProt (P21675)
Pfam (PF00439)
Homo sapiens (Human)Cell cycle gene 1 protein, TBP-associated factor 250 kDa, p250, Transcription initiation factor TFIID 250 kDa subunit, TAFII250
2B
(A)
N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamidenon-polymer295.31Chemie (67B)
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4D
(A)
waterwater18.0281Chemie (HOH)
Sequence modifications
A: 1497 - 1638 (UniProt: P21675)
PDBExternal DatabaseDetails
Gly 1495-expression tag
Ser 1496-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16576.6
Non-Polymers*Number of molecules2
Total formula weight335.4
All*Total formula weight16912.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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