5HXU
Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Barbiturase | polymer | 389 | 41188.2 | 2 | UniProt (Q8RSQ2) Pfam (PF09663) | Rhodococcus erythropolis | |
| 2 | C, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | D, I (A, B) | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID | non-polymer | 190.2 | 2 | Chemie (MHA) | |||
| 4 | E, J (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | F, K (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 617 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 369 (UniProt: Q8RSQ2)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 287 | Asn 287 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82376.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 785.4 | |
| All* | Total formula weight | 83161.7 |
