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5HXS

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Sr2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
sodium,calcium exchangerpolymer30032029.11UniProt (Q57556)
Pfam (PF01699)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
2B, C
(A)
STRONTIUM IONnon-polymer87.62Chemie (SR)
3D, E, F, G, H...
(A)
PENTADECANEnon-polymer212.47Chemie (MYS)
4K
(A)
2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYLnon-polymer164.21Chemie (TOE)
5L, M
(A)
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoatenon-polymer356.52Chemie (OLC)
6N
(A)
waterwater18.010Chemie (HOH)
Sequence modifications
A: 1 - 300 (UniProt: Q57556)
PDBExternal DatabaseDetails
Val 2Leu 2engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32029.1
Non-Polymers*Number of molecules12
Total formula weight2539.4
All*Total formula weight34568.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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