5HXP
Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic | polymer | 233 | 26783.8 | 2 | UniProt (B8XA40) Pfam (PF01255) | Solanum habrochaites (Wild tomato) | Z,Z-FPP synthase,Z-farnesyl pyrophosphate synthase |
| 2 | C, G, H (A, C) | ISOPENTYL PYROPHOSPHATE | non-polymer | 248.1 | 3 | Chemie (IPR) | |||
| 3 | D (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | E, F (C) | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | non-polymer | 264.3 | 2 | Chemie (O4B) | |||
| 5 | I, J (A, C) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A, C: 72 - 303 (UniProt: B8XA40)
| PDB | External Database | Details |
|---|---|---|
| Met 71 | - | initiating methionine |
| Ala 75 | Glu 75 | engineered mutation |
| Tyr 103 | His 103 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53567.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1297.3 | |
| All* | Total formula weight | 54864.8 |
