5HX4

Zinc-Free APOBEC3F Catalytic Domain Crystal Structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA dC->dU-editing enzyme APOBEC-3F	polymer	199	23361.1	2	UniProt (Q8IUX4) Pfam (PF08210)	Homo sapiens (Human)	Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F,A3F
2	C, D (A, B)	water	water		18.0	117	Chemie (HOH)

Sequence modifications

A, B: 185 - 373 (UniProt: Q8IUX4)

PDB	External Database	Details
Gly 175	-	expression tag
Pro 176	-	expression tag
Leu 177	-	expression tag
Gly 178	-	expression tag
Ser 179	-	expression tag
Pro 180	-	expression tag
Gly 181	-	expression tag
Ile 182	-	expression tag
Pro 183	-	expression tag
Gly 184	-	expression tag
Asp 196	Tyr 196	engineered mutation
Gly 247	His 247	engineered mutation
Arg 248	Cys 248	engineered mutation
Ala 259	Cys 259	engineered mutation
Lys 302	Phe 302	engineered mutation
Asp 310	Trp 310	engineered mutation
Asp 355	Lys 355	engineered mutation
Asp 358	Lys 358	engineered mutation
Asp 363	Phe 363	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46722.2
All*	Total formula weight	46722.2

*Water molecules are not included.