5HUK

The crystal structure of neuraminidase from A/Northern pintail/Washington/40964/2014 influenza virus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Neuraminidase	polymer	402	44117.8	4	UniProt (A0A0C4WXC5) Pfam (PF00064)	Influenza A virus (A/Northern pintail/Washington/40964/2014(H5N2))
2	E, F, H, J, L (E, F, H, J, L)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
3	G, I, K, M (G, I, K, M)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	4	In PDB GlyTouCan (G07617FP)
4	N, O, Q, S (A, B, C, D)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
5	P, R, T (B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	U, V, W, X (A, B, C, D)	water	water		18.0	389	Chemie (HOH)

Sequence modifications

A, B, C, D: 83 - 469 (UniProt: A0A0C4WXC5)

PDB	External Database	Details
Ser 68	-	expression tag
Leu 69	-	expression tag
Val 70	-	expression tag
Pro 71	-	expression tag
Arg 72	-	expression tag
Gly 73	-	expression tag
Ser 74	-	expression tag
Gly 75	-	expression tag
Asp 76	-	expression tag
Ser 77	-	expression tag
Gly 78	-	expression tag
Ser 79	-	expression tag
Pro 80	-	expression tag
Gly 81	-	expression tag
Ala 82	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	176471.4
Branched	Number of molecules	9
	Total formula weight	7062.4
Non-Polymers*	Number of molecules	7
	Total formula weight	823.9
All*	Total formula weight	184357.7

*Water molecules are not included.