5HU0

BACE1 in complex with 4-(3-(furan-2-carboxamido)phenyl)-1-methyl-5-oxo-4-phenylimidazolidin-2-iminium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-secretase 1	polymer	412	45979.6	2	UniProt (P56817) Pfam (PF00026)	Homo sapiens (Human)	Aspartyl protease 2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2
2	C, E (A, B)	L(+)-TARTARIC ACID	non-polymer		150.1	2	Chemie (TLA)
3	D, F (A, B)	N-{3-[(2E,4R)-2-imino-1-methyl-5-oxo-4-phenylimidazolidin-4-yl]phenyl}furan-2-carboxamide	non-polymer		374.4	2	Chemie (66H)
4	G, H (A, B)	water	water		18.0	925	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91959.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1049.0
All*	Total formula weight	93008.1

*Water molecules are not included.