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5HS6

Human 17beta-hydroxysteroid dehydrogenase type 14 in complex with Estrone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
17-beta-hydroxysteroid dehydrogenase 14polymer27428682.71UniProt (Q9BPX1)
Pfam (PF13561)
Homo sapiens (Human)17-beta-HSD 14,17-beta-hydroxysteroid dehydrogenase DHRS10,Dehydrogenase/reductase SDR family member 10,Retinal short-chain dehydrogenase/reductase retSDR3,Short chain dehydrogenase/reductase family 47C member 1
2B
(A)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.41Chemie (NAD)
3C
(A)
(9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-onenon-polymer270.41Chemie (J3Z)
4D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5E
(A)
waterwater18.0136Chemie (HOH)
Sequence modifications
A: 1 - 270 (UniProt: Q9BPX1)
PDBExternal DatabaseDetails
Gly -1-expression tag
His 0-expression tag
Gly 271-expression tag
Ser 272-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28682.7
Non-Polymers*Number of molecules3
Total formula weight956.8
All*Total formula weight29639.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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