5HQ6
Crystal structure of fragment bound with Brd4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 125 | 14841.2 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B (A) | (2R)-2,6-dimethyl-2H-1,4-benzoxazin-3(4H)-one | non-polymer | 177.2 | 1 | Chemie (64R) | |||
| 3 | C (A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 44 - 166 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14841.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 177.2 | |
| All* | Total formula weight | 15018.4 |
