5HPW
Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lactoperoxidase | polymer | 595 | 67529.8 | 4 | UniProt (A3F9D6) Pfam (PF03098) UniProt (by SIFTS) (A0A452E9Y6) | Capra hircus (Goat) | |
| 2 | E, G, H (E, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G79924RM) | |||
| 4 | FA, GA, I, J, Q... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 5 | HA, K, R, Z (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 6 | AA, BA, CA, IA, JA... (C, D, A, B) | NITRATE ION | non-polymer | 62.0 | 12 | Chemie (NO3) | |||
| 7 | DA, LA, O, W (C, D, A, B) | 6-propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one | non-polymer | 170.2 | 4 | Chemie (3CJ) | |||
| 8 | EA, MA, P, V (C, D, A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 9 | NA, OA, PA, QA (A, B, C, D) | water | water | 18.0 | 651 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 270119.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 5599.7 | |
| All* | Total formula weight | 277416.4 |
