5HPU

Insulin with proline analog HyP at position B28 in the R6 state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Insulin, chain A	polymer	21	2383.7	2	UniProt (P01308) In PDB	Homo sapiens (Human)
2	B, D	Insulin, chain B	polymer	30	3450.0	2	UniProt (P01308) Pfam (PF00049) In PDB	Homo sapiens (Human)
3	A, C	PHENOL	non-polymer		94.1	2	Chemie (IPH)
4	B, D	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	B, D	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6		water	water		18.0	17	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	11667.3
Non-Polymers*	Number of molecules	6
	Total formula weight	389.9
All*	Total formula weight	12057.2

*Water molecules are not included.