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5HPK

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase NEDD4-likepolymer38345251.51UniProt (Q96PU5)
Pfam (PF00632)
Homo sapiens (Human)NEDD4.2,Nedd4-2
2B
(B)
Ubiquitin variant NL.1polymer8610050.51Pfam (PF00240)
UniProt (by SIFTS) (P62987)
Homo sapiens (Human)
3C, D
(A, B)
waterwater18.0131Chemie (HOH)
Sequence modifications
A: 574 - 955 (UniProt: Q96PU5)
PDBExternal DatabaseDetails
Gly 573-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55302.0
All*Total formula weight55302.0
*Water molecules are not included.

239492

PDB entries from 2025-07-30

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