5HO8
DISCOVERY OF NOVEL 7-AZAINDOLES AS PDK1 INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 3-phosphoinositide-dependent protein kinase 1 | polymer | 309 | 35427.6 | 1 | UniProt (O15530) Pfam (PF00069) In PDB | Homo sapiens (Human) | hPDK1 |
| 2 | A | 4-butyl-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | non-polymer | 267.3 | 1 | Chemie (63E) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35427.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 651.6 | |
| All* | Total formula weight | 36079.2 |
