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5HNY

Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tubulin alpha-1B chainpolymer43848638.81UniProt (P81947)
Pfam (PF00091)
Pfam (PF03953)
Bos taurus (Bovine)Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2B
(B)
Tubulin beta-2B chainpolymer42647809.71UniProt (Q6B856)
Pfam (PF00091)
Pfam (PF03953)
Bos taurus (Bovine)Beta-tubulin
3C
(K)
Protein claret segregational, Kinesin-1/Kinesin-14, Protein claret segregationalpolymer37141720.41UniProt (P20480)
Pfam (PF00225)
UniProt (by SIFTS) (P56536)
Drosophila melanogaster (Fruit fly)
4D
(A)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
5E, H
(A, K)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6F
(B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
7G
(B)
TAXOLnon-polymer853.91Chemie (TA1)
8I
(K)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
Sequence modifications
A: 2 - 439 (UniProt: P81947)
PDBExternal DatabaseDetails
Ser 136Leu 136conflict
Gly 232Ser 232conflict
Gly 265Ile 265conflict
Thr 340Ser 340conflict
Glu 358Gln 358conflict
B: 2 - 437 (UniProt: Q6B856)
PDBExternal DatabaseDetails
Ala 57Thr 55conflict
Val 172Met 170conflict
Ala 298Ser 296conflict
Val 318Ile 316conflict
K: 1 - 24 (UniProt: P20480)
K: 25 - 341 (PDB: 5HNY)
K: 340 - 371 (UniProt: P20480)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight138169.0
Non-Polymers*Number of molecules6
Total formula weight2375.1
All*Total formula weight140544.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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