5HNX
Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tubulin alpha-1B chain | polymer | 451 | 50107.2 | 1 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B | Tubulin beta-2B chain | polymer | 445 | 49907.8 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (Bovine) | Beta-tubulin |
| 3 | K | Protein claret segregational,kinesin-1/kinesin-14,Protein claret segregational | polymer | 371 | 41620.3 | 1 | UniProt (P20480) Pfam (PF00225) UniProt (by SIFTS) (P56536) In PDB | Drosophila melanogaster (Fruit fly) | |
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 6 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 7 | B | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) |
Sequence modifications
A: 1 - 451 (UniProt: P81947)
B: 1 - 455 (UniProt: Q6B856)
K: 1 - 24 (UniProt: P20480)
K: 25 - 334 (PDB: 5HNX)
K: 335 - 371 (UniProt: P20480)
| PDB | External Database | Details |
|---|---|---|
| Ser 136 | Leu 136 | conflict |
| Gly 232 | Ser 232 | conflict |
| Gly 265 | Ile 265 | conflict |
| Thr 340 | Ser 340 | conflict |
| Glu 358 | Gln 358 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 55 | conflict |
| Val 172 | Met 170 | conflict |
| Ala 298 | Ser 296 | conflict |
| Val 318 | Ile 316 | conflict |
K: 25 - 334 (PDB: 5HNX)
K: 335 - 371 (UniProt: P20480)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 141635.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1844.6 | |
| All* | Total formula weight | 143479.9 |
