5HNW
Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the AMPPNP state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tubulin alpha-1B chain | polymer | 450 | 49976.0 | 1 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B (B) | Tubulin beta-2B chain | polymer | 444 | 49776.6 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 3 | C (K) | Protein claret segregational,KINESIN HEAVY CHAIN ISOFORM 5C | polymer | 371 | 41620.3 | 1 | UniProt (P20480) Pfam (PF00225) UniProt (by SIFTS) (P56536) | Drosophila melanogaster (Fruit fly) | ncd,KIF5C,ncd |
| 4 | D, H (A, K) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | E (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 6 | F (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 7 | G (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) PubChem (16757828) PubChem (16760674) PubChem (4666) PubChem (21458255) PubChem (23307219) PubChem (23412627) PubChem (23636632) PubChem (16760177) PubChem (16742549) PubChem (24848897) PubChem (24867246) PubChem (21733096) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (44323108) PubChem (44356961) PubChem (44403716) PubChem (24754091) PubChem (24207713) PubChem (24791027) PubChem (25200067) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (46781469) PubChem (44279927) PubChem (44335735) PubChem (44291178) PubChem (44328863) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (49868078) PubChem (45489039) PubChem (46782671) PubChem (54259298) PubChem (71209844) PubChem (57908851) PubChem (57946364) PubChem (58803237) PubChem (53313247) PubChem (53298534) PubChem (54259297) PubChem (59844545) PubChem (54259299) PubChem (59904698) PubChem (60123443) PubChem (57489669) PubChem (57999380) PubChem (58460861) PubChem (58777027) PubChem (58798493) PubChem (58596717) PubChem (59048611) PubChem (59042813) PubChem (58877402) PubChem (60005248) PubChem (59873251) PubChem (59914794) PubChem (59919147) PubChem (60123436) PubChem (60011010) PubChem (60147315) PubChem (66795656) PubChem (70943371) PubChem (71096818) PubChem (5460441) PubChem (14060298) PubChem (176586897) PubChem (177678861) PubChem (73759783) PubChem (36314) PubChem (60915) PubChem (177409) PubChem (184492) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (441276) PubChem (9854162) PubChem (73707502) PubChem (73759704) PubChem (9897470) PubChem (10033513) PubChem (10485732) PubChem (11506104) PubChem (89493063) PubChem (11828953) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (14060309) PubChem (15983941) PubChem (91885464) PubChem (5317123) PubChem (5321715) PubChem (101920282) PubChem (5352019) PubChem (121459571) PubChem (122361554) PubChem (101598423) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (124747272) PubChem (124893098) PubChem (9875988) PubChem (126968948) PubChem (129395998) PubChem (129627423) PubChem (10748131) PubChem (132517454) PubChem (118528174) PubChem (11320430) PubChem (11354895) PubChem (134368714) PubChem (134972678) PubChem (124747271) PubChem (124747273) PubChem (124747274) PubChem (137705323) PubChem (138106885) PubChem (126761000) PubChem (140731501) PubChem (140512017) PubChem (133052515) PubChem (133640187) PubChem (146034004) PubChem (153289350) PubChem (154037993) PubChem (134715514) PubChem (155982214) PubChem (159121804) PubChem (160053861) PubChem (159716711) PubChem (160171678) PubChem (160585530) PubChem (163077211) PubChem (163077212) PubChem (163077209) PubChem (163284947) PubChem (143890766) PubChem (168322423) PubChem (152743329) PubChem (169917882) PubChem (171036874) PubChem (154828192) PubChem (144453087) PubChem (160585532) PubChem (175758871) PubChem (163077210) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (165084161) PubChem (166711459) PubChem (167423928) PubChem (170014955) PubChem (170362150) | |||
| 8 | I (K) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) |
Sequence modifications
A: 2 - 451 (UniProt: P81947)
B: 2 - 455 (UniProt: Q6B856)
K: 1 - 24 (UniProt: P20480)
K: 25 - 334 (PDB: 5HNW)
K: 335 - 371 (UniProt: P20480)
| PDB | External Database | Details |
|---|---|---|
| Ser 136 | Leu 136 | conflict |
| Gly 232 | Ser 232 | conflict |
| Gly 265 | Ile 265 | conflict |
| Thr 340 | Ser 340 | conflict |
| Glu 358 | Gln 358 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 55 | conflict |
| Val 172 | Met 170 | conflict |
| Ala 298 | Ser 296 | conflict |
| Val 318 | Ile 316 | conflict |
K: 25 - 334 (PDB: 5HNW)
K: 335 - 371 (UniProt: P20480)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 141372.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2375.1 | |
| All* | Total formula weight | 143748.0 |
