5HNA
Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1251
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Farnesyl pyrophosphate synthase, putative | polymer | 375 | 43784.2 | 4 | UniProt (A5K4U6) Pfam (PF00348) | Plasmodium vivax | |
| 2 | E, F, G, H (A, B, C, D) | 4-chloro-2-{[3-(decyloxy)-5-hydroxybenzyl]oxy}-5-sulfamoylbenzoic acid | non-polymer | 514.0 | 4 | Chemie (63D) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 22 - 396 (UniProt: A5K4U6)
| PDB | External Database | Details |
|---|---|---|
| Met 134 | Thr 113 | conflict |
| Asp 227 | Asn 206 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 175136.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2056.1 | |
| All* | Total formula weight | 177192.9 |
