5HLS
Crystal structure of the first bromodomain of human BRD4 bound to CPI-0610
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 128 | 15126.3 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A | CPI-0610 | non-polymer | 365.8 | 1 | Chemie (62G) | |||
| 3 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 42 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15126.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 365.8 | |
| All* | Total formula weight | 15492.2 |
