5HLN
X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH CHIR99021
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glycogen synthase kinase-3 beta | polymer | 424 | 47179.5 | 2 | UniProt (P49841) Pfam (PF00069) In PDB | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
2 | A, B | CHIR99021 | non-polymer | 465.3 | 2 | Chemie (65C) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) |
Sequence modifications
A, B: 1 - 420 (UniProt: P49841)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Pro -1 | - | expression tag |
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 94359.0 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1369.8 | |
All* | Total formula weight | 95728.7 |