5HJ9

Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Arginase	polymer	330	36034.4	1	UniProt (Q6TUJ5) Pfam (PF00491)	Leishmania mexicana
2	B, C (A)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	D (A)	[(5R)-5-amino-5-carboxy-7-(piperidin-1-yl)heptyl](trihydroxy)borate(1-)	non-polymer		303.2	1	Chemie (X7A)
4	E (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	F (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	G, H, I (A)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
7	J, K (A)	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
8	L (A)	water	water		18.0	200	Chemie (HOH)

Sequence modifications

A: 13 - 329 (UniProt: Q6TUJ5)

PDB	External Database	Details
Met 0	-	expression tag
Arg 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Gly 10	-	expression tag
Met 11	-	expression tag
Ala 12	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36034.4
Non-Polymers*	Number of molecules	10
	Total formula weight	1087.8
All*	Total formula weight	37122.2

*Water molecules are not included.