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5HHI

Structure of human DNA polymerase beta Host-Guest complexed with CBZ-platinated N7-G

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32937536.81UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3')polymer164998.21synthetic construct
3C
(P)
DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3')polymer102931.91synthetic construct
4D
(D)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01synthetic construct
5E, F
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
6G
(P)
platinum(4+) chloride azanide [2-(9H-carbazol-9-yl)ethyl]azanide (1:1:2:1)non-polymer471.81Chemie (61C)
7H, I, J, K
(A, T, P, D)
waterwater18.036Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47003.0
Non-Polymers*Number of molecules3
Total formula weight517.8
All*Total formula weight47520.8
*Water molecules are not included.

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PDB entries from 2026-01-14

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