5HFR
Crystal structure of the second bromodomain H395R mutant of human BRD3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bromodomain-containing protein 3 | polymer | 113 | 13326.4 | 4 | UniProt (Q15059) Pfam (PF00439) In PDB | Homo sapiens (Human) | RING3-like protein |
| 2 | A | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 3 | B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 402 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 306 - 416 (UniProt: Q15059)
| PDB | External Database | Details |
|---|---|---|
| Ser 304 | - | expression tag |
| Met 305 | - | expression tag |
| Arg 395 | His 395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53305.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 310.3 | |
| All* | Total formula weight | 53616.1 |
