5HFB

The third PDZ domain from the synaptic protein PSD-95 (H372A mutant) in complex with a C-terminal peptide derived from CRIPT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Disks large homolog 4	polymer	119	12671.0	1	UniProt (P31016) Pfam (PF00595) In PDB	Rattus norvegicus (Rat)	Postsynaptic density protein 95,PSD-95,Synapse-associated protein 90,SAP90
2	B	Cysteine-rich PDZ-binding protein	polymer	9	1070.2	1	UniProt (Q792Q4) In PDB	Rattus norvegicus	Cysteine-rich interactor of PDZ three,Cysteine-rich interactor of PDZ3
3		water	water		18.0	148	Chemie (HOH)

Sequence modifications

A: 302 - 402 (UniProt: P31016)

PDB	External Database	Details
Gly 297	-	expression tag
Ser 298	-	expression tag
Pro 299	-	expression tag
Glu 300	-	expression tag
Phe 301	-	expression tag
Ala 372	His 372	engineered mutation
Asn 403	-	expression tag
Ser 404	-	expression tag
Arg 405	-	expression tag
Val 406	-	expression tag
Asp 407	-	expression tag
Ser 408	-	expression tag
Ser 409	-	expression tag
Gly 410	-	expression tag
Arg 411	-	expression tag
Ile 412	-	expression tag
Val 413	-	expression tag
Thr 414	-	expression tag
Asp 415	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13741.2
All*	Total formula weight	13741.2

*Water molecules are not included.