5HE3
Bovine GRK2 in complex with Gbetagamma subunits and CCG224411
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Beta-adrenergic receptor kinase 1 | polymer | 641 | 74778.1 | 1 | UniProt (P21146) Pfam (PF00615) Pfam (PF00069) Pfam (PF00169) In PDB | Bos taurus (Bovine) | Beta-ARK-1, G-protein-coupled receptor kinase 2 |
2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (Human) | Transducin beta chain 1 |
3 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (Human) | G gamma-I |
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | (4~{S})-4-[3-[2-(2,6-dimethylphenyl)ethylcarbamoyl]-4-fluoranyl-phenyl]-~{N}-(1~{H}-indazol-5-yl)-6-methyl-2-oxidanylidene-3,4-dihydro-1~{H}-pyrimidine-5-carboxamide | non-polymer | 540.6 | 1 | Chemie (FF1) | |||
6 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 119925.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 564.9 | |
All* | Total formula weight | 120489.9 |