5HDO
Crystal structure of a nanobody raised against urokinase-type plasminogen activator
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Anti-HCV NS3/4A serine protease immoglobulin heavy chain | polymer | 128 | 13598.0 | 4 | UniProt (A0A0F6YEF6) Pfam (PF07686) In PDB | Camelus dromedarius (Dromedary) | |
2 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | B, C, D | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 127 (UniProt: A0A0F6YEF6)
PDB | External Database | Details |
---|---|---|
Gln 1 | Glu 1 | conflict |
Gln 5 | Val 5 | conflict |
Leu 11 | Ser 11 | conflict |
Phe 27 | Tyr 27 | conflict |
Leu 29 | Tyr 29 | conflict |
Asp 30 | Cys 30 | conflict |
Ala 33 | Gly 33 | conflict |
Ile 34 | Met 34 | conflict |
Gly 35 | Ser 35 | conflict |
Phe 37 | Tyr 37 | conflict |
Gly 47 | Phe 47 | conflict |
Cys 50 | Ala 50 | conflict |
Ser 52 | - | insertion |
Ala 53 | Asp 52 | conflict |
Gly 55 | Asp 54 | conflict |
Asn 59 | Ser 58 | conflict |
Arg 72 | Gln 71 | conflict |
Lys 87 | Ile 86 | conflict |
Ser 88 | Pro 87 | conflict |
Val 93 | Met 92 | conflict |
Ala 97 | Lys 96 | conflict |
Ala 98 | Thr 97 | conflict |
His 100 | Gln 99 | conflict |
Pro 101 | Thr 100 | conflict |
Leu 103 | - | insertion |
Cys 104 | - | insertion |
Thr 105 | Gly 102 | conflict |
Glu 107 | Trp 104 | conflict |
Ser 108 | Trp 105 | conflict |
Gly 109 | Ala 106 | conflict |
Arg 110 | Asp 107 | conflict |
Arg 111 | Cys 108 | conflict |
Gln 122 | Met 119 | conflict |
Ala 128 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 54391.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 526.1 | |
All* | Total formula weight | 54917.9 |