5HBV
Complex structure of Fab35 and mouse nAChR alpha1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-bungarotoxin isoform V31 | polymer | 74 | 8033.3 | 1 | UniProt (P60616) Pfam (PF21947) | Bungarus multicinctus (Many-banded krait) | BGTX V31,Long neurotoxin 1 |
| 2 | B (B) | Acetylcholine receptor subunit alpha 1 | polymer | 212 | 24729.0 | 1 | UniProt (P04756) Pfam (PF02931) | Mus musculus (Mouse) | |
| 3 | C (C) | Fab35, Light Chain | polymer | 213 | 23393.0 | 1 | Rattus norvegicus (Norway rat) | ||
| 4 | D (D) | Fab35, Heavy Chain | polymer | 219 | 23879.8 | 1 | Rattus norvegicus (Norway rat) | ||
| 5 | E (E) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 1 | In PDB GlyTouCan (G68668TB) | |||
| 6 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
B: 2 - 211 (UniProt: P04756)
| PDB | External Database | Details |
|---|---|---|
| Lys 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Glu 8 | Val 28 | engineered mutation |
| Arg 149 | Trp 169 | engineered mutation |
| Ala 155 | Val 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 80035.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1559.4 | |
| All* | Total formula weight | 81594.5 |
