5H9Q

Crystal Structure of Human Galectin-7 in Complex with TD139

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Galectin-7	polymer	155	17137.2	2	UniProt (P47929) Pfam (PF00337)	Homo sapiens (Human)	Gal-7,HKL-14,PI7,p53-induced gene 1 protein
2	C (B)	3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside	non-polymer		648.6	1	Chemie (TD2)
3	D, E (A, B)	water	water		18.0	256	Chemie (HOH)

Sequence modifications

A, B: 0 - 135 (UniProt: P47929)

PDB	External Database	Details
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34274.4
Non-Polymers*	Number of molecules	1
	Total formula weight	648.6
All*	Total formula weight	34923.1

*Water molecules are not included.