5H7G

Crystal structure of the BCL6 BTB domain in complex with F1324

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	B-cell lymphoma 6 protein	polymer	141	16287.7	2	UniProt (P41182) Pfam (PF00651)	Homo sapiens (Human)	BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51
2	C, D (C, D)	F1324 peptide	polymer	13	1725.0	2		Enterobacteria phage T7
3	E, F (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	G, H, I, J (A, B, C, D)	water	water		18.0	89	Chemie (HOH)

Sequence modifications

A, B: 5 - 129 (UniProt: P41182)

PDB	External Database	Details
Leu -11	-	expression tag
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Glu -2	-	expression tag
Asn -1	-	expression tag
Leu 0	-	expression tag
Tyr 1	-	expression tag
Phe 2	-	expression tag
Gln 3	-	expression tag
Gly 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	36025.5
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	36217.6

*Water molecules are not included.