5H77

Crystal structure of the PKA-protein A fusion protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A	polymer	90	10314.5	12	UniProt (P13861) UniProt (P38507) Pfam (PF02197) Pfam (PF02216)	Homo sapiens (Human)	IgG-binding protein A,Staphylococcal protein A

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 2 - 38 (UniProt: P13861)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Pro 0	-	expression tag
Trp 1	-	expression tag

A, B, C, D, E, F, G, H, I, J, K, L: 39 - 87 (UniProt: P38507)

PDB	External Database	Details
Arg 41	Asn 222	engineered mutation
Ala 59	Gly 240	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	123774.3
All*	Total formula weight	123774.3

*Water molecules are not included.