5GVX

Structural insight into dephosphorylation by Trehalose 6-phosphate Phosphatase (OtsB2) from Mycobacterium Tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Trehalose-phosphate phosphatase	polymer	430	45948.9	1	UniProt (P9WFZ5) Pfam (PF02358)	Mycobacterium tuberculosis	TPP,Trehalose-6-phosphate phosphatase
2	B (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	C (A)	water	water		18.0	38	Chemie (HOH)

Sequence modifications

A: 2 - 391 (UniProt: P9WFZ5)

PDB	External Database	Details
Met -38	-	expression tag
Gly -37	-	expression tag
Ser -36	-	expression tag
Ser -35	-	expression tag
His -34	-	expression tag
His -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
Ser -28	-	expression tag
Ser -27	-	expression tag
Gly -26	-	expression tag
Leu -25	-	expression tag
Val -24	-	expression tag
Pro -23	-	expression tag
Arg -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
Met -18	-	expression tag
Ala -17	-	expression tag
Ser -16	-	expression tag
Met -15	-	expression tag
Thr -14	-	expression tag
Gly -13	-	expression tag
Gly -12	-	expression tag
Gln -11	-	expression tag
Gln -10	-	expression tag
Met -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Glu -4	-	expression tag
Phe -3	-	expression tag
Glu -2	-	expression tag
Leu -1	-	expression tag
Val 0	-	expression tag
Val 1	-	expression tag
Met 29	Leu 29	engineered mutation
Met 133	Leu 133	engineered mutation
Lys 271	Glu 271	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45948.9
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	45973.2

*Water molecules are not included.