5GRL
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | polymer | 339 | 36682.2 | 1 | UniProt (P50213) Pfam (PF00180) | Homo sapiens (Human) | Isocitric dehydrogenase subunit alpha,NAD(+)-specific ICDH subunit alpha |
| 2 | B (B) | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial | polymer | 354 | 38867.5 | 1 | UniProt (P51553) Pfam (PF00180) | Homo sapiens (Human) | Isocitric dehydrogenase subunit gamma,NAD(+)-specific ICDH subunit gamma |
| 3 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | D (B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (B) | ISOCITRIC ACID | non-polymer | 192.1 | 1 | Chemie (ICT) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75549.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 667.9 | |
| All* | Total formula weight | 76217.6 |
