5GIH
Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-phenylethylamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dopamine N-acetyltransferase | polymer | 215 | 24428.0 | 1 | UniProt (Q94521) Pfam (PF13673) | Drosophila melanogaster (Fruit fly) | Arylalkylamine N-acetyltransferase,aaNAT1 |
| 2 | B (A) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 3 | C (A) | N-(2-phenylethyl)acetamide | non-polymer | 163.2 | 1 | Chemie (54W) | |||
| 4 | D (A) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A: 21 - 230 (UniProt: Q94521)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Asp 47 | Glu 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24428.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 930.8 | |
| All* | Total formula weight | 25358.8 |
