5GIG
Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dopamine N-acetyltransferase | polymer | 215 | 24428.0 | 1 | UniProt (Q94521) Pfam (PF13673) In PDB | Drosophila melanogaster (Fruit fly) | Arylalkylamine N-acetyltransferase,aaNAT1 |
| 2 | A | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 3 | A | ~{N}-[2-[3,4-bis(oxidanyl)phenyl]ethyl]ethanamide | non-polymer | 195.2 | 1 | Chemie (7DP) | |||
| 4 | A | (4S,5S)-1,2-DITHIANE-4,5-DIOL | non-polymer | 152.2 | 1 | Chemie (D1D) | |||
| 5 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 21 - 230 (UniProt: Q94521)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Asp 47 | Glu 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24428.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1115.0 | |
| All* | Total formula weight | 25543.0 |
