5GGP

Crystal structure of N-terminal domain of human protein O-mannose beta-1,2-N-acetylglucosaminyltransferase in complex with GlcNAc-beta1,2-Man-peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	polymer	164	17623.0	2	UniProt (Q8WZA1) Pfam (PF15711) In PDB	Homo sapiens (Human)	POMGnT1,UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2,GnT I.2
2	C, D	10-mer Peptide from Dystroglycan	polymer	10	927.1	2	UniProt (Q14118) In PDB	Homo sapiens	Dystrophin-associated glycoprotein 1
3	E, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose	branched		383.3	2	In PDB GlyTouCan (G85856KC)
4	A, B	SODIUM ION	non-polymer		23.0	5	Chemie (NA)
5		water	water		18.0	278	Chemie (HOH)

Sequence modifications

A, B: 92 - 250 (UniProt: Q8WZA1)

PDB	External Database	Details
Gly 87	-	expression tag
Pro 88	-	expression tag
Leu 89	-	expression tag
Gly 90	-	expression tag
Ser 91	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37100.1
Branched	Number of molecules	2
	Total formula weight	766.7
Non-Polymers*	Number of molecules	5
	Total formula weight	114.9
All*	Total formula weight	37981.8

*Water molecules are not included.