5GG6

Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hydrolase, NUDIX family protein	polymer	342	38153.1	2	UniProt (A0QUZ2) Pfam (PF00293) Pfam (PF00300)	Mycobacterium smegmatis str. MC2 155	MutT1
2	C, J (A, B)	8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (8DG)
3	D, K (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E, F, L, M, N (A, B)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
5	G, H, I (A)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	O, P (A, B)	water	water		18.0	543	Chemie (HOH)

Sequence modifications

A, B: 1 - 322 (UniProt: A0QUZ2)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76306.3
Non-Polymers*	Number of molecules	12
	Total formula weight	1458.4
All*	Total formula weight	77764.7

*Water molecules are not included.