5G3W
Structure of HDAC like protein from Bordetella Alcaligenes in complex with the photoswitchable inhibitor CEW65
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE | polymer | 374 | 40122.3 | 4 | UniProt (Q70I53) Pfam (PF00850) | BORDETELLA | HDAC-LIKE AMIDOHYDROLASE, HDAH |
| 2 | AA, E, L, T (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | BA, CA, F, G, M... (D, A, B, C) | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) | |||
| 4 | EA, FA, GA, H, I... (D, A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 11 | Chemie (PEG) | |||
| 5 | DA, K, S, W (D, A, B, C) | (2E)-N-hydroxy-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-enamide | non-polymer | 267.3 | 4 | Chemie (C65) | |||
| 6 | P, Y (B, C) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 7 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 1791 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 369 (UniProt: Q70I53)
| PDB | External Database | Details |
|---|---|---|
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Pro 251 | His 251 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 160489.1 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 3287.4 | |
| All* | Total formula weight | 163776.6 |
