5G06
Cryo-EM structure of yeast cytoplasmic exosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EXOSOME COMPLEX COMPONENT RRP45 | polymer | 305 | 34001.9 | 1 | UniProt (Q05636) Pfam (PF01138) Pfam (PF03725) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RIBOSOMAL RNA-PROCESSING PROTEIN 45 |
| 2 | B (B) | EXOSOME COMPLEX COMPONENT SKI6 | polymer | 246 | 27599.7 | 1 | UniProt (P46948) Pfam (PF01138) Pfam (PF03725) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | EXTRACELLULAR MUTANT PROTEIN 20, RIBOSOMAL RNA-PROCESSING PROTEIN 41, SUPERKILLER PROTEIN 6 |
| 3 | C (C) | EXOSOME COMPLEX COMPONENT RRP43 | polymer | 394 | 44093.0 | 1 | UniProt (P25359) Pfam (PF01138) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RIBOSOMAL RNA-PROCESSING PROTEIN 43 |
| 4 | D (D) | EXOSOME COMPLEX COMPONENT RRP46 | polymer | 223 | 24430.2 | 1 | UniProt (P53256) Pfam (PF01138) Pfam (PF03725) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RIBOSOMAL RNA-PROCESSING PROTEIN 46 |
| 5 | E (E) | EXOSOME COMPLEX COMPONENT RRP42 | polymer | 265 | 29099.2 | 1 | UniProt (Q12277) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RIBOSOMAL RNA-PROCESSING PROTEIN 42 |
| 6 | F (F) | EXOSOME COMPLEX COMPONENT MTR3 | polymer | 250 | 27590.0 | 1 | UniProt (P48240) Pfam (PF01138) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | MRNA TRANSPORT REGULATOR 3 |
| 7 | G (G) | EXOSOME COMPLEX COMPONENT RRP40 | polymer | 240 | 26583.4 | 1 | UniProt (Q08285) Pfam (PF21262) Pfam (PF15985) Pfam (PF18311) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RIBOSOMAL RNA-PROCESSING PROTEIN 40 |
| 8 | H (H) | EXOSOME COMPLEX COMPONENT RRP4 | polymer | 359 | 39470.2 | 1 | UniProt (P38792) Pfam (PF14382) Pfam (PF21266) Pfam (PF15985) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RIBOSOMAL RNA-PROCESSING PROTEIN 4 |
| 9 | I (I) | EXOSOME COMPLEX COMPONENT CSL4 | polymer | 292 | 31619.3 | 1 | UniProt (P53859) Pfam (PF21551) Pfam (PF10447) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | CEP1 SYNTHETIC LETHAL PROTEIN 4 |
| 10 | J (J) | EXOSOME COMPLEX EXONUCLEASE DIS3 | polymer | 1001 | 113855.8 | 1 | UniProt (Q08162) Pfam (PF13638) Pfam (PF17216) Pfam (PF17849) Pfam (PF00773) Pfam (PF17215) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | CHROMOSOME DISJUNCTION PROTEIN 3, RIBOSOMAL RNA-PROCESSING PROTEIN 44 |
| 11 | K (P) | SUPERKILLER PROTEIN 7 | polymer | 747 | 84888.7 | 1 | UniProt (Q08491) Pfam (PF00009) Pfam (PF21921) Pfam (PF21920) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | CYTOPLASMIC EXOSOME COMPONENT SKI7 |
Sequence modifications
C: 1 - 394 (UniProt: P25359)
E: 1 - 265 (UniProt: Q12277)
F: 1 - 250 (UniProt: P48240)
J: 1 - 1001 (UniProt: Q08162)
| PDB | External Database | Details |
|---|---|---|
| Met 363 | Val 363 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ile 138 | Val 138 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 75 | Thr 75 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asn 171 | Asp 171 | conflict |
| Asn 551 | Asp 551 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 483231.2 | |
| All* | Total formula weight | 483231.2 |
