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5FZT

The crystal structure of R7R8 in complex with a DLC1 fragment.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
TALIN-1polymer30932574.71UniProt (P26039)
Pfam (PF21896)
MUS MUSCULUS (HOUSE MOUSE)
2B
(B)
RHO GTPASE-ACTIVATING PROTEIN 7polymer232803.21UniProt (Q96QB1)HOMO SAPIENSDELETED IN LIVER CANCER 1 PROTEIN, DLC-1, HP PROTEIN, RHO-TYPE GTPASE-ACTIVATING PROTEIN 7, START DOMAIN-CONTAINING PROTEIN 12, STARD12, STAR-RELATED LIPID TRANSFER PROTEIN 12, DLC1
3C, D
(B)
MALONATE IONnon-polymer102.02Chemie (MLI)
4E, F
(A, B)
waterwater18.0165Chemie (HOH)
Sequence modifications
A: 1359 - 1659 (UniProt: P26039)
PDBExternal DatabaseDetails
Gly 1351-expression tag
Ile 1352-expression tag
Asp 1353-expression tag
Pro 1354-expression tag
Phe 1355-expression tag
Thr 1356-expression tag
Lys 1357-expression tag
His 1358-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35377.9
Non-Polymers*Number of molecules2
Total formula weight204.1
All*Total formula weight35582.0
*Water molecules are not included.

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PDB entries from 2026-03-25

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