5FZN
Structure of the Keap1 Kelch domain in complex with a small molecule inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | polymer | 304 | 33362.3 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) | MUS MUSCULUS (HOUSE MOUSE) | CYTOSOLIC INHIBITOR OF NRF2, INRF2, KEAP1 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | benzenesulfonamide | non-polymer | 157.2 | 1 | Chemie (FB2) | |||
| 4 | D (A) | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A: 322 - 624 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Gly 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33362.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 253.3 | |
| All* | Total formula weight | 33615.5 |
