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5FZJ

Structure of the Keap1 Kelch domain in complex with a small molecule inhibitor.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AKELCH-LIKE ECH-ASSOCIATED PROTEIN 1polymer30433362.31UniProt (Q9Z2X8)
Pfam (PF01344)
In PDB
MUS MUSCULUS (HOUSE MOUSE)CYTOSOLIC INHIBITOR OF NRF2, INRF2, KEAP1
2A2,6-DIMETHYL-4H-PYRANO[3,4-D][1,3]OXAZOL-4-ONEnon-polymer165.11Chemie (75K)
3waterwater18.0266Chemie (HOH)
Sequence modifications
A: 322 - 624 (UniProt: Q9Z2X8)
PDBExternal DatabaseDetails
Gly 321-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33362.3
Non-Polymers*Number of molecules1
Total formula weight165.1
All*Total formula weight33527.4
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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