5FYX
Crystal structure of Drosophila NCS-1 bound to penothiazine FD16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FREQUENIN 2 | polymer | 187 | 21922.4 | 1 | UniProt (Q9VWX8) Pfam (PF00036) Pfam (PF13499) | DROSOPHILA MELANOGASTER (FRUIT FLY) | |
| 2 | B, C, D (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | E, F, G, H, I... (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 6 | Chemie (MPD) | |||
| 4 | K (A) | N-[2-(2-chloranylphenothiazin-10-yl)ethyl]-4-methyl-piperazin-1-amine | non-polymer | 374.9 | 1 | Chemie (FD6) | |||
| 5 | L (A) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 1 - 187 (UniProt: Q9VWX8)
| PDB | External Database | Details |
|---|---|---|
| Met 178 | Ile 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21922.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1204.2 | |
| All* | Total formula weight | 23126.7 |
