5FY9
Crystal structure of the catalytic domain of human JARID1B in complex with pyruvate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LYSINE-SPECIFIC DEMETHYLASE 5B, LYSINE-SPECIFIC DEMETHYLASE 5B | polymer | 479 | 55214.3 | 1 | UniProt (Q9UGL1) Pfam (PF02375) Pfam (PF02373) Pfam (PF21323) Pfam (PF02928) In PDB | HOMO SAPIENS (HUMAN) | |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 6 | A | PYRUVIC ACID | non-polymer | 88.1 | 1 | Chemie (PYR) | |||
| 7 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 26 - 101 (UniProt: Q9UGL1)
A: 374 - 770 (UniProt: Q9UGL1)
| PDB | External Database | Details |
|---|---|---|
| Ser 24 | - | expression tag |
| Met 25 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 102 | - | linker |
| Gly 371 | - | linker |
| Gly 372 | - | linker |
| Gly 373 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55214.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1180.6 | |
| All* | Total formula weight | 56394.9 |
