5FY9
Crystal structure of the catalytic domain of human JARID1B in complex with pyruvate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | LYSINE-SPECIFIC DEMETHYLASE 5B, LYSINE-SPECIFIC DEMETHYLASE 5B | polymer | 479 | 55214.3 | 1 | UniProt (Q9UGL1) Pfam (PF02375) Pfam (PF02373) Pfam (PF21323) Pfam (PF02928) In PDB | HOMO SAPIENS (HUMAN) | |
2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
6 | A | PYRUVIC ACID | non-polymer | 88.1 | 1 | Chemie (PYR) | |||
7 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 26 - 101 (UniProt: Q9UGL1)
A: 374 - 770 (UniProt: Q9UGL1)
PDB | External Database | Details |
---|---|---|
Ser 24 | - | expression tag |
Met 25 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 102 | - | linker |
Gly 371 | - | linker |
Gly 372 | - | linker |
Gly 373 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 55214.3 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1180.6 | |
All* | Total formula weight | 56394.9 |